The use of biomaterial composed by β-TCP and PLGA in regenerative treatment of Grade II furca injuries in mandibular molars - literature review

Abstract

Objective: This study aims to evaluate a biomaterial composed of β-TCP and PLGA in regenerative treatment of furcation grade II in mandibular molars. Method: Scientific studies published between 2000 and 2020 in English and Portuguese were used in the PubMed, Scielo and Semantic Scholar databases. The search in the database resulted in 84 articles and after reading and analyzing them, 23 papers were selected that met the objective of this literature review. Discussion: Non-absorbable materials limit bone formation and the biological mechanisms that configure the tissue healing process, even in grafting situations. Thus, alloplastic or resorbable materials are increasingly used as bone substitutes, as they are biologically compatible with adjacent tissues, in addition to inducing bone growth and remodeling, maintaining homeostasis and the essential characteristics of bone tissues. Among the biomaterials cited, β-TCP and PLGA, demonstrated satisfactory results in tissue and bone regeneration guided in cases of furcation and grafting procedures, as they present ideal characteristics, such as biocompatibility, bioreabsorption and osteoconduction. Conclusion: Beta-tricalcium phosphate in union with PLGA (vitaGraft), is a viable material for grafting procedures and / or periodontal regeneration of furcation lesions in mandibular posterior teeth.